The two different methods, both offer you, the player, the same user experience and the only difference is in the back end of how the online lottery ticket provider works. The two methods that online lottery sites use differ in one key way; They either have agents and employees all over the world that physically purchase tickets on behalf of clients or, the more recent phenomenon is when companies essentially take out an insurance policy on every ticket which is tied to the size of the jackpot. This is the difference between you playing the lottery online and betting on the lottery online*. In the latter option you are, de facto, not playing the US Powerball online but rather you are placing a bet with an insurance company on the outcome of the corresponding Powerball draw. 
Powerball numbers are drawn from two sets of numbers, so the odds of winning a prize are calculated by combining the odds for both sets of numbers for all prize levels. The odds for matching just the Powerball are calculated by combining the odds of selecting the Powerball and the odds of not selecting any of the five numbers from the first set of numbers drawn.
The structure of the draw is one which regular lottery players will be very familiar with; players must pick 5 regular numbers from a pool with a total of 69 numbers and in addition to these regular number picks, you also choose one bonus ball (known as the Powerball) from a pool of 26. These two pools of numbers are mutually exclusive and remain completely separate throughout the drawing procedure. In order to jackpot the US Powerball, you need to match all 5 regular numbers and the Powerball. Do this and you are instant Powerball millionaire – it’s as simple as that!
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