The probability and odds can be taken into a mathematical perspective: The probability of winning the jackpot (through October 27, 2017) was 1:(75C5) x (15); that is: 75 ways for the first white ball times 74 ways for the second times 73 for the third times 72 for the fourth times 71 for the last white ball divided by 5 x 4 x 3 x 2 x 1, or 5!, and this number is then multiplied by 15 (15 possible numbers for the "Megaball"). Therefore, (75 x 74 x 73 x 72 x 71)/ (5 x 4 x 3 x 2 x 1) x 15 = 258,890,850, which means any combination of five white balls plus the Megaball has a 1:258,890,850 chance of winning the jackpot. Similarly, the odds for second prize are 1:(75C5) x (15/14) = 1: 18,492,204 chance of winning. The overall probability of winning any prize was 1 in 14.7. If there are no jackpot winners for a specific drawing, the jackpot will keep increasing, however, the odds will still remain the same.

^{Two machines are used in each Mega Millions drawing. The model used for Mega Millions is the Criterion II, manufactured by Smartplay International of Edgewater Park, New Jersey. The balls are moved around by means of counter-rotating arms which randomly mix the balls. Individually, the five white balls, several seconds apart, drop through a hole in the bottom of the mixing drum. }

On May 18, 2013, the world's largest one-ticket jackpot, an annuity of approximately $590.5 million ($620 million today), was won by a Powerball ticket sold in Zephyrhills, Florida.[33] On June 5, Florida Lottery officials announced the winner: Gloria C. MacKenzie, 84, who purchased the "quick pick" ticket at a Publix supermarket.[34] MacKenzie chose the cash option of approximately $370.8 million, before Federal withholding; Florida does not have a state income tax.[34]

`The US Powerball is a standard lottery draw game based and operated from the golden State of California. The US Powerball has been making millionaires and multi-millionaires since its first drawing way back in 1992. With over 25 years of experience in the lottery industry, the Powerball, along with many other State lotteries, has broken through the final glass ceiling and transformed itself from an interstate lottery into a truly international lottery of global reach.`